My guess is it will be something network/firewall related.
Win10 can be a nightmare for certain things randomly not working, and due to the mix of simple settings screens and old detailed settings, finding the right option can be challenging. Even with the firewall seemingly completely disabled, some connections still refuse to work.

I had to run an entire event over wifi once, because Win10 on my laptop simply refused to let me use a wired connection and connect to the required software from other laptops. Then when I got home and tried it to try and work out what the problem was, it worked perfectly. I still don't know what the problem was, and it's worked fine ever since :-/