The door interlock will switch off all mains power to the control cabinet, if I need to turn off power other than this the plug socket has a trip/reset switch.

Yes drives fault will be part of the e-stop circuit....just trying to work out how to implement it all through a Pilz relay (and now contactors, any suggestions as to a good contactor to use?) and into the CSMIO IP/M.

My thoughts (so far!!) is that any E-stop (1 on control panel and 1 on machine), limit switch, AM882 + Kinco fault, (VFD fault, not sure if the Huanyang Inverter has this yet, but presume so, as not read the manual), stop button on control panel kills all power to the 70V PSU (and so the AM882 drives) & 230V Kinco Nema 34 driver. Need to work out how to shut down the spindle, presume by sending Mach3 a signal which then tells the VFD to stop the spindle?

I'll put a switch on the cabinet front panel to isolate the 24V supply only, do you remove 24V power from everything or just the Pilz relay?