Hi there and welcome...

A quick Google suggests HME Technology is an educational/small systems supplier so these would originally have come as a complete setup with PC/Software etc. The R50 is no longer listed as far as I can see and a quick google gets nothing back either :( . Without knowing more about it connectivity, etc. its hard to give exact answers. generally you'll need a program like MAch3 to drive the positioning system, but configuring that needs some info about the internals of the box...or some experience and trial and error.... once thats working then the rest is relatively easy...

From the picture I'd say these are low end machines for primarily plastics/engraving or light alloy use rather than anything more industrial.