This is excatly where i'm going with my machine simply because it'll suit my workshop more. My latest design has the longest axis of 2m on the gantry using 2 or 3 lengths of 60x60x5 stacked on top of each other with an ali back plate and using a rotating ballnut to drive it on a 2510 screw.
But then am i sacrificing rigidity of the machine just to make it easier for me to access.....?