That's a good question Wilfy & something that I am not sure about either although I did purchase a breakout board from diycnc. The uniport V2 I know I could have bought a board cheaper as I don't need most of the functions on it but had no idea what to get.
The drivers I have are already protected so no need for the opto isolation, the spindle will run through the super Pid so no need for the spindle relay, 5v supply will be from an old computer power supply so no need for the usb connection. Probably other things as well, it wasn't a cheap board at all I just didn't know anything about them when I bought it.