No you need to set a Zero work position and return to that not Home position. Reason being that home position is referencing a switch so it will and should always return to that position.
Returning to Zero work position will tell you if you have lost position thru missed steps or slipping couplings etc.

But before all this have you Surfaced the Bed.? . . . . With fine engraving you can't have any error in the bed.!