Aluminum router build - Could use some input

[Washout]

If you are using ali extrusion for your frame then you may be able to get some ideas from my build here: http://www.mycncuk.com/threads/5139-It-s-begun
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Some caveats though - my machine is compromised by using the round supported rails. Its not useless by any means, but not as good as using profiled guides/rails and bearings (especially on the Z and Y axis). I think your rails should also be mounted differently (especially X axis).
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Most guys on here also go for a welded steel frame, as it is cheaper, generally stronger, but of course you may not have someone who can weld it for you (I also did not at the time).
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Oh also consider using twin X axis ballscrews (one on each side).
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I'm sure you get tons of advice and best of luck with the build.